Matching DNA variants to medicines takes scarce experts.
Cogenics turns variant-to-drug interpretation into a query, grounded in published prescribing guidelines.
From DNA variant to the right medicine.
Cogenics maps a patient's DNA variants to how they will respond to a medicine — grounded in CPIC prescribing guidelines and ClinVar, and built to run as a small specialized model.
Why it exists
Problems we are solving
Genotype-guided prescribing works, but does not scale.
A Lancet study of 7,000 patients found it cut adverse drug reactions by about 30%. Cogenics is built to make that guidance available beyond specialist centres.
Grounding
CPIC prescribing guidelines define what a correct answer is; ClinVar is the reference variant dataset. Every variant-to-drug association is validated against these sources before it becomes training material.
How it is measured
Following the PGxAI Andromeda validation template: blinded expert review plus guideline-adherence scoring, with gene-drug pair coverage tracked alongside accuracy.
What it does
Grounded in the guidelines.
Variant to medicine
Maps DNA variants to medicine compatibility and expected response.
Guideline-grounded
Answers trace back to CPIC prescribing guidelines, not to model intuition.
Validated sources
Variant-to-drug associations are checked against ClinVar before training.
Small and local
A specialized model that serves through Ember on hardware you control.
Process
How it is built
Validate
Variant-to-drug associations are checked against CPIC and ClinVar.
Train
A small specialized model is trained on the validated associations only.
Measure
Blinded expert review and guideline-adherence scoring, published with stated limits.
Access
Follow Cogenics
Cogenics is validating its variant-to-drug associations before training. Follow it for validation results and research partnerships.
Follow Cogenics- On release
Model
Pharmacogenomics model
Requirements
- Validated variant-drug associations
Questions / answers
Cogenics FAQ
What is Cogenics?
Cogenics maps patient DNA variants to medicine compatibility, grounded in CPIC prescribing guidelines and ClinVar.
What makes an answer trustworthy?
Every association is validated against published guidelines before training, and the model is measured by blinded expert review.
Is this medical advice?
No. Cogenics is a research tool, not a clinical product, and makes no diagnostic or treatment claims.
Models are served through Ember, on hardware we control.